POTENTIAL MODERATORS OF PHYSICAL ACTIVITY ON BRAIN HEALTH

Potential Moderators of Physical Activity on Brain Health

Age-related cognitive decline is linked to numerous molecular, structural, and functional changes in the brain.However, physical activity is a promising method of reducing unfavorable age-related changes.Physical activity exerts its effects on the brain through many molecular pathways, some of which are regulated by genetic variants in humans.In th

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The outpatient management of hypertension at two Sierra Leonean health centres: A mixed-method investigation of follow-up compliance and patient-reported barriers to care

Background: Sub-Saharan Africa faces an increasing burden of non-communicable diseases.In particular, hypertension and its therapeutic control present a challenge and opportunity for health practitioners and health systems within the region.Aim: This study sought to assess an initiative conducted by two health clinics to begin treatment of hyperten

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10H-1,9-diazaphenothiazine and its 10-derivatives: synthesis, characterisation and biological evaluation as potential anticancer agents

10H-1,9-diazaphenothiazine was obtained in the sulphurisation Breast reaction of diphenylamine with elemental sulphur and transformed into new 10-substituted derivatives, containing alkyl and dialkylaminoalkyl groups at the thiazine nitrogen atom.The 1,9-diazaphenothiazine ring system was identified with advanced 1H and 13C NMR techniques (COSY, NO

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